α-PVP (also known as α-Pyrrolidinopentiophenone, α-pyrrolidinovalerophenone, α-PVP, O-2387, β-keto-prolintane, prolintanone, or desmethylpyrovalerone) is a synthetic stimulant of the cathinone class developed in the 1960s that has been sold as a designer drug.
alpha-Pyrrolidinovalerophenone (also known as α-PVP, A-PVP, alpha-PVP, and Flakka) is a synthetic stimulant substance of the cathinone and pyrrolidine chemical classes. It produces medium-lived cathinone-like stimulation and disinhibition with a pronounced euphoric “rush” component when administered.
α-PVP is chemically similar to other pyrrolidine compounds such as MDPV and to other cathinone compounds found in the khat shrub of eastern Africa. It generally comes in the form of either a crystalline powder or crystallized shards which users can ingest to produce powerful but short-lived euphoric stimulant effects which are comparable to those of methamphetamine and cocaine when insufflated or vaporized.
α-PVP has been subject to much scrutiny by the media, similar to how MDPV and “bath salts” were portrayed in early 2011. Very little data exists about the pharmacological properties, metabolism, and toxicity of a-PVP and it has little history of human usage. It is commonly mass produced in China and commercially distributed as a research chemical by online vendors.
Due to its potent psychostimulant effects, dependence and addiction-producing potential and toxicity profile if misused, it is highly advised that one take proper precautions, conduct sufficient independent research, and use proper harm reduction practices if choosing to use with this substance.
α-PVP, or alpha-Pyrrolidinovalerophenone, is a compound of the substituted cathinone and substituted pyrrolidine chemical classes. Its structure is comprised of pentanal bound to a phenyl ring at the 1 position and the nitrogen of a pyrrolidine ring at the 2 position. α-PVP acts as a potent norepinephrine-dopamine reuptake inhibitor (NDRI), similar to the designer drug MDPV.
The effects listed below are based upon the subjective effects index and personal experiences of PsychonautWiki contributors. The listed effects should be taken with a grain of salt and will rarely (if ever) occur all at once, but heavier doses will increase the chances and are more likely to induce a full range of effects