3-FPM (also known as 3-Fluorophenmetrazine, 3F-Phenmetrazine or PAL-593) is a phenylmorpholine-based stimulant and fluorinated analogue of phenmetrazine
3-Fluorophenmetrazine (also called 3F-Phenmetrazine, 3-FPM or PAL-593) is a stimulant substance of the phenylmorpholine chemical class. It produces classical stimulant effects such as stimulation, focus & motivation enhancement, thought acceleration, wakefulness, and euphoria when administered. It is a structural analog of phenmetrazine, a once-popular stimulant drug that was clinically used as an anorectic (weight-loss agent) in Europe in the 1950s before it was later withdrawn due to concerns over misuse and addiction.
According to anecdotal reports, 3-FPM is considered to be more subtle in its effects when compared to other stimulants and produces less nervousness, euphoria, and insomnia than substances of the substituted amphetamine class, leading to its adoption as a study and productivity-enhancing drug as opposed to the more typical recreational stimulant with pronounced euphoric properties.
It should be noted that although this compound is usually sold under the name “3-FPM”, it was first named in scientific literature as “PAL-593”. Using this name to search for information regarding this compound may be more successful than using “3-FPM.”
Very little data exists about the pharmacological properties, metabolism, and toxicity of 3-FPM in humans. It has no history of human usage until 2014 when it began being sold as a gray-area research chemical by online vendors. Due to its likely ability to produce dependence and addiction, it is highly advised to use harm reduction practices if choosing to use this substance.
3-Fluorophenmetrazine (3-FPM) is a synthetic molecule of the amphetamine family. Molecules of the amphetamine class contain a phenethylamine core featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain with an additional methyl substitution at Rα. Amphetamines are alpha-methylated phenethylamines. 3-FPM contains a fluorine atom attached at R3 of the phenyl ring. Additionally, part of its amphetamine skeleton is incorporated into a morpholine ring. At R2 of its chain, an oxygen group is bound — this oxygen group is linked by an ethyl chain to the terminal amine of the amphetamine chain to form a morpholine group. 3-FPM is a fluorinated derivative of phenmetrazine.