5-MeO-MiPT is a psychedelic and hallucinogenic drug, used by some as an entheogen. It has structural and pharmacodynamic properties similar to the drugs 5-MeO-DiPT, DiPT, and MiPT. It is commonly used as a “substitute” for 5-MeO-DiPT because of the very similar structure and effects.
5-Methoxy-N-methyl-N-isopropyltryptamine (also known as 5-MeO-MiPT or colloquially as Moxy) is a lesser-known psychedelic substance of the tryptamine class that produces psychedelic effects when administered. It is structurally related to tryptamines like MiPT, 4-HO-MiPT, and 5-MeO-DiPT.
5-MeO-MiPT has no history of human usage prior to the 1985 publication of its synthesis and pharmacology by Repke, Grotjahn & Shulgin.
Anecdotal reports characterize the effects of this compound as highly stimulating and mildly entactogenic, lacking in typical psychedelic visual distortions. Many users report strong physical and tactile effects that serve to enhance libido and sexual pleasure. An unpleasant body load is also often reported at higher dosages.
Very little is known about the pharmacological properties, metabolism and toxicity of this substance, and it has a limited history of human use. It has been sold online as a research chemical. It is highly advised to use harm reduction practices if using this substance.
5-MeO-MiPT or 5-methoxy-N-methyl-N-isopropyltryptamine is a synthetic indole alkaloid molecule of the tryptamine class. Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R3 to an amino group via an ethyl side chain. 5-MeO-MiPT is substituted at R5 of its indole heterocycle with a methoxy (MeO) functional group CH3O−; it also contains a methyl group and an isopropyl chain bound to the terminal amine RN of its tryptamine backbone (MiPT). 5-MeO-MiPT is the N-substituted isopropyl homologue of 5-MeO-DMT.
5-MeO-MiPT’s psychedelic effects are believed to come from its efficacy at the 5-HT2A receptor as a partial agonist and additional mechanisms of action such as the inhibition of MAO (i.e. digestive enzymes in the stomach) have also been speculated upon, though this has yet to be demonstrated scientifically.